Ageless Medicine

 Restylane

Restylane Pictures courtesy of Resylane

Where can Restylane® be used?

Restylane® has been used in more than one million treatments in over 60 countries to correct a variety of wrinkles and to enhance the appearance of the lip border. It is currently approved in the U.S. for the treatment of facial wrinkles and folds, such as nasolabial folds, which are the lines from the nose to the corners of the mouth.

BEFORE and AFTER Treatment

Individual results may vary

BeforeAfter BeforeAfter

                          Before                                              After                                                      Before                                                  After

What is Restylane®?

Restylane® is a safe and natural cosmetic dermal filler that restores volume and fullness to the skin to correct facial wrinkles and folds, such as nasolabial folds.


Courtesy of Restylane


Restylane® is the only cosmetic dermal filler made of non-animal-based hyaluronic acid, a natural substance that already exists in the human body. The hyaluronic acid in Restylane® is a crystal-clear gel called NASHA™ or Non-Animal Stabilized Hyaluronic Acid. NASHA is completely biocompatible with human hyaluronic acid.

Restylane® maintains its shape using the body's own moisture. The hyaluronic acid in Restylane® is hydrophilic or "water loving." As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide lasting results.

Unlike other hyaluronic acid-based products, such as those made from rooster combs, only Restylane® is non-animal-based. This quality virtually eliminates any risk of animal-based disease transmission or allergic reaction.

How long does Restylane® last?

Clinical studies have shown the average Restylane® treatment results can last six months or even longer3. The unique NASHA™ technology helps maintain the cosmetic effect until the injected material is nearly gone.

Restylane® is proven to deliver a longer lasting effect than traditional collagen3, so treatments are typically scheduled twice a year. (Individual results may vary.)

What to Expect?

Restylane® does not require any pretesting but you should take a few precautions before being treated. You should avoid using aspirin, non-steroidal anti-inflammatory medication, St. John's Wort, or high doses of Vitamin E supplements for one week prior to treatment because they may increase bruising or bleeding at the injection site. Also, if you have previously suffered from facial cold sores, there is a risk that the needle punctures could contribute to another recurrence.

Restylane® is injected directly into the skin in tiny amounts by an ultrafine needle, resulting in minimal discomfort. The procedure is simple and convenient and results are practically instantaneous. To optimize your comfort during the short procedure, your physician may decide to numb the treatment area.

Is Restylane® safe?

Since 1996, over one million Restylane® treatments have been safely administered by dermatologists and plastic surgeons in more than 60 countries. This innovative treatment is now approved in the U.S. for the treatment of facial wrinkles and folds.

Restylane® has a highly favorable safety profile. It's composed of Non-Animal Stabilized Hyaluronic Acid (NASHA™) a substance found naturally in the human body. Restylane® is fully biocompatible. There is virtually no risk of animal-based disease transmission or allergic reaction, so no allergy testing is required before use.

Based on clinical studies3, Restylane® treatments produce a very low occurrence of adverse events. The most commonly reported side effects were temporary redness and swelling at the injection site. These effects typically resolve within two to three days.

What are the advantage of Restylane?

Restylane® is different from Botox®.

Restylane® is a natural, cosmetic filler. Botox® is a drug that blocks nerve transmission and relaxes the underlying muscles. Many patients have been very pleased after receiving treatment with both products.

Restylane® is different than other hyaluronic acid-based products.

Unlike other hyaluronic acid-based products, such as those made from rooster combs, only Restylane® is non-animal based. This quality virtually eliminates any risk of animal-based disease transmission or allergic reaction.

Restylane® is different from bovine collagen.

Restylane® is proven to deliver a longer lasting effect than traditional collagen3 with virtually no risk of animal-based disease transmission or allergic reaction. Bovine collagen is derived from cowhide and requires an allergy test. Restylane® can be administered without pretesting, so no waiting is required.

What are the Post-Treatment Instructions?

Please observe the following after treatment with Restylane®.

Immediately after the treatment, the most commonly reported side effects were temporary redness and swelling at the injection site. These effects typically resolve within two to three days. Cold compresses may be used immediately after the treatment to reduce swelling. If the inconvenience continues beyond two to three days or if other reactions occur, please contact your physician.
Avoid touching the treated area within six hours of your treatment. After that, the area can be gently washed with soap and water.
Until the initial redness and swelling have resolved, avoid exposure of the treated area to intense heat (sunlamp or sunbathing).
If you have previously suffered from facial cold sores, there is a risk that the needle punctures could contribute to another recurrence. Speak to your physician about medications that may minimize a recurrence.
Avoid exercise and alcohol for six hours after your treatment.
Evidence shows that having a follow-up treatment before the product has fully dissipated will enhance the lasting effect. Please be sure to consult your physician about recommendations for follow-up treatments.
For one week prior to your next treatment with Restylane, avoid taking aspirin, non-steroidal anti-inflammatory medications, St. John's Wort, and high doses of Vitamin E supplements. These agents may increase bruising and bleeding at the injection site.

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