Restylane
Where can Restylane® be used?
Restylane® has been used in more than one million treatments in over 60
countries to correct a variety of wrinkles and to enhance the appearance of the
lip border. It is currently approved in the U.S. for the treatment of facial
wrinkles and folds, such as nasolabial folds, which are the lines from the nose
to the corners of the mouth.
BEFORE and AFTER Treatment
Individual results may vary



Before After Before After
What is Restylane®?
Restylane® is a safe and natural cosmetic dermal filler that
restores volume and fullness to the skin to correct facial wrinkles
and folds, such as nasolabial folds.


Restylane® is the only cosmetic dermal filler made of
non-animal-based hyaluronic acid, a natural substance that already
exists in the human body. The hyaluronic acid in Restylane® is a
crystal-clear gel called NASHA™ or Non-Animal Stabilized Hyaluronic
Acid. NASHA is completely biocompatible with human hyaluronic acid.
Restylane® maintains its shape using the body's own moisture. The
hyaluronic acid in Restylane® is hydrophilic or "water loving." As
hyaluronic acid gradually degrades, each molecule binds to more
water and over time, the same volume can be maintained with less
hyaluronic acid. This ability of hyaluronic acid to bind to water is
what helps provide lasting results.
Unlike other hyaluronic acid-based products, such as those made from
rooster combs, only Restylane® is non-animal-based. This quality
virtually eliminates any risk of animal-based disease transmission
or allergic reaction.
How long does Restylane® last?
Clinical studies have shown the average Restylane® treatment results
can last six months or even longer3. The unique NASHA™ technology
helps maintain the cosmetic effect until the injected material is
nearly gone.
Restylane® is proven to deliver a longer lasting effect than
traditional collagen3, so treatments are typically scheduled twice a
year. (Individual results may vary.)
What to Expect?
Restylane® does not require any pretesting but you should take a few
precautions before being treated. You should avoid using aspirin,
non-steroidal anti-inflammatory medication, St. John's Wort, or high
doses of Vitamin E supplements for one week prior to treatment
because they may increase bruising or bleeding at the injection
site. Also, if you have previously suffered from facial cold sores,
there is a risk that the needle punctures could contribute to
another recurrence.
Restylane® is injected directly into the skin in tiny amounts by an
ultrafine needle, resulting in minimal discomfort. The procedure is
simple and convenient and results are practically instantaneous. To
optimize your comfort during the short procedure, your physician may
decide to numb the treatment area.
Is Restylane® safe?
Since 1996, over one million Restylane® treatments have been safely
administered by dermatologists and plastic surgeons in more than 60
countries. This innovative treatment is now approved in the U.S. for
the treatment of facial wrinkles and folds.
Restylane® has a highly favorable safety profile. It's composed of
Non-Animal Stabilized Hyaluronic Acid (NASHA™) a substance found
naturally in the human body. Restylane® is fully biocompatible.
There is virtually no risk of animal-based disease transmission or
allergic reaction, so no allergy testing is required before use.
Based on clinical studies3, Restylane® treatments produce a very low
occurrence of adverse events. The most commonly reported side
effects were temporary redness and swelling at the injection site.
These effects typically resolve within two to three days.
What are the advantage of Restylane?
Restylane® is different from Botox®.
Restylane® is a natural, cosmetic filler. Botox® is a drug that
blocks nerve transmission and relaxes the underlying muscles. Many
patients have been very pleased after receiving treatment with both
products.
Restylane® is different than other hyaluronic acid-based products.
Unlike other hyaluronic acid-based products, such as those made from
rooster combs, only Restylane® is non-animal based. This quality
virtually eliminates any risk of animal-based disease transmission
or allergic reaction.
Restylane® is different from bovine collagen.
Restylane® is proven to deliver a longer lasting effect than
traditional collagen3 with virtually no risk of animal-based disease
transmission or allergic reaction. Bovine collagen is derived from
cowhide and requires an allergy test. Restylane® can be administered
without pretesting, so no waiting is required.
What are the Post-Treatment Instructions?
Please observe the following after treatment with Restylane®.
Immediately after the treatment, the most commonly reported side
effects were temporary redness and swelling at the injection site.
These effects typically resolve within two to three days. Cold
compresses may be used immediately after the treatment to reduce
swelling. If the inconvenience continues beyond two to three days or
if other reactions occur, please contact your physician.
Avoid touching the treated area within six hours of your treatment.
After that, the area can be gently washed with soap and water.
Until the initial redness and swelling have resolved, avoid exposure
of the treated area to intense heat (sunlamp or sunbathing).
If you have previously suffered from facial cold sores, there is a
risk that the needle punctures could contribute to another
recurrence. Speak to your physician about medications that may
minimize a recurrence.
Avoid exercise and alcohol for six hours after your treatment.
Evidence shows that having a follow-up treatment before the product
has fully dissipated will enhance the lasting effect. Please be sure
to consult your physician about recommendations for follow-up
treatments.
For one week prior to your next treatment with Restylane, avoid
taking aspirin, non-steroidal anti-inflammatory medications, St.
John's Wort, and high doses of Vitamin E supplements. These agents
may increase bruising and bleeding at the injection site.
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